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Browsing Auburn University Graduate School by Author "Upton, Jason"
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Characterization of RHIM Domain Functionality in Viral Pathogens Through Interaction with Necroptotic Machinery
Haich, Rachel (2025-07-30)
Necroptotic cell death occurs following cellular stress conditions in which there is a
potential benefit to the host to encouraging an inflammatory response. Often, this is an additional
defense against pathogens, although ...
Classical Techniques in an Unconventional System: Investigation of the Insect Immune System and Gut Microbiome
Boyer-Millander, Faith (2024-12-05) ETD File Embargoed
The role of the gut microbiome in development and function of the host immune system has long been an area of interest, investigated across taxa for decades. As mammalian systems can sometimes provide a prohibitive challenge ...
From Proteins to People: Cytomegalovirus Modulation of Host Cellular Responses and Its Implications on Health Equity
Brahms, Olivia (2025-12-09) ETD File Embargoed
Human cytomegalovirus (CMV) is one of the nine known human herpesviruses that causes significant disease burden in the developed world. As a natural pathogen in mice, murine CMV (MCMV) serves as an ideal animal model to ...
IE3: The Viral Sensation
Yates, Shawn (2024-12-08) ETD File Embargoed
Herpesviruses are ubiquitous DNA viruses that have been detected in every human population tested. These viruses have left their mark across the animal kingdom and are highly species-specific. Herpesviruses have the ability ...
Resisting Resistance: Development of Nanoparticle-mediated Delivery Systems to Explore RNA Interference as a Solution to Biological Resistance
McGraw, Erin (2025-04-22) ETD File Embargoed
Biological resistance to conventional pesticides and antifungals presents a significant challenge in agriculture and healthcare, necessitating the development of alternative control strategies. RNA interference (RNAi) ...