Auburn University Graduate School: Recent submissions
Now showing items 501-520 of 9366
Nanoplasmonic On-Chip Immunoassay for Precision Immune Profiling
(2024-02-20)
A comprehension of the immune system is essential for precise prognosis and effective treatment of immune-related disorders. The practice of precision immune profiling is pivotal for personalized monitoring, disease ...
Immunoproteasome Inhibitors for the Treatment of MLL-AF4 ALL
(2024-02-15)
Acute lymphoblastic leukemia, ALL, is a cancer of the blood or bone marrow that develops from the uncontrolled proliferation of lymphocytes. One subtype of ALL is caused by a translocation involving the MLL gene, or mixed ...
Integrated Spatial and Social Network Analysis of Conflict Impacts on Food Production in Eastern Ukraine; A Geospatial Perspective
(2024-01-26)
Ukraine-Russian geopolitical relations over the years have experienced periods of tranquility and violence with conflicts since 1917, including the events of the 2014 annexation of Crimea and the 2022 Russian invasion of ...
The Effect of Grid Resolution on Hydrodynamic Modeling of Biscayne Bay
(2024-01-08)
Environmental Fluid Dynamics Code Plus (EFDC+) is a model that has been proven to be effective in hydrodynamic simulation. Understanding water surface elevation (WSE) and salinity dynamics in estuaries is crucial for ...
Training Pharmacists to Implement Depression Screening Services
(2024-01-08)
Background: Depression is the leading cause of disability in persons over 15 years old. It is estimated that over 7% of people have depression but only 40-50% of those actually receive treatment. Inadequate treatment has ...
Four Essays in International Trade and Economic Development
(2024-01-08)
This dissertation comprises four essays investigating the impact of trade agreements on trade outcomes and the relationship between export diversification and economic growth.
Chapter 1 investigates the effect of the ...
Estimation of Relative Motion between Non-Rigid Bodies on a Semi-Truck
(2024-01-08)
This thesis develops methods to estimate the relative motion between the cabin and chassis
of a semi-truck without the use of a complex suspension model between the two bodies. In,
this thesis only sensors that would be ...
Deep Integration of a Flight Vehicle Dynamic Model in a Vector Tracking Software Defined Receiver
(2024-01-04)
The greater occurrence of signal interference on Global Navigation Satellite Systems
(GNSS) requires additional alternative navigation solutions to provide robust, reliable localization
of flight vehicles when measurements ...
Integrating a Simple Photometric System with Programmable Droplet Formation for Quantification of Diabetes Biomarkers and to Study Adipose Tissue Secretions
(2023-12-14)
The chapters presented within this dissertation give a comprehensive account of the development and adaptation of cost-effective optical components tailored for integration into microfluidic devices, with a primary focus ...
Biochemical production from engineered Bacillus species
(2023-12-12)
Microbial production of biochemicals has gained significant attention due to increasing global concern regarding the depletion of fossil resources. As prominent workhorses in microbial fermentations, Bacillus species have ...
Novel mechanism of inhibition of the proteasome by Bruton’s Tyrosine Kinase inhibitors
(2023-12-12)
Bruton’s tyrosine kinase (BTK) inhibitor Ibrutinib has been shown to synergize in vitro with proteasome inhibitors (PIs) in reducing the viability of cells derived from B-cell malignancies. This synergy was also observed ...
Guidelines of Transferring Brutalist Architectural Styles from Mid-20th Century To Furniture Design
(2023-12-11)
This thesis explores how to transfer mid-20th-century architectural styles into furniture design to create furniture that harmonizes with the architecture itself. This thesis discusses the concept of applying mid-20th-century ...
Math Developmental Education Practices in the Alabama Community College System: Fall 2012 to Summer 2022
(2023-12-11)
In the United States, students often graduate from high school unprepared to succeed in college. In Alabama, fewer than 25% of high school graduates are college ready. Frequently, unprepared students enroll in community ...
Mathematics Enrichment through Accelerated Learning to improve Learning and Achievement for PreK-12 students in Alabama
(2023-12-11)
The most recent nationwide math scores for 13-year-olds in the US dropping to the lowest level in decades, including Alabama's placement at the bottom, as revealed by the 2019 nationwide NAEP assessment, highlight the ...
Performance Evaluation of Sediment Control Practices
(2023-12-11)
Sediment is a major pollutant of waterways, increasing turbidity, carrying other harmful pollutants, and reducing flow capacity, which can lead to loss of aquatic life and increased risk of flooding. Construction projects, ...
Branched Amphiphilic Peptide Capsules (BAPCs): A promising platform for mRNA therapeutics delivery.
(2023-12-11)
mRNA therapeutics represent an emerging and powerful strategy for the treatment and
prevention of infectious and genetic diseases. However, mRNA molecules are large anionic
polymer that necessitate a delivery vector to ...
Riluzole prodrug alters hippocampal glutamatergic function: a mechanism for the amelioration of synaptic plasticity and memory deficits observed in a preclinical Alzheimer’s disease model
(2023-12-11)
Glutamate-mediated hippocampal hyperexcitability has been linked to the progression of Alzheimer’s disease (AD). Previous research suggests that drugs aimed at mediating glutamate dysregulation may also be useful AD ...
Eight weeks of supplementation with Vitamin D3 improves serum concentrations but does not affect strength or body composition in young-adult resistance training females
(2023-12-11)
Various lines of evidence suggest vitamin D exerts a range of beneficial effects in skeletal muscle. Nonetheless, there are limited and mixed data regarding the efficacy of vitamin D supplementation on body composition and ...
Open-Graded Friction Courses Suitable for Suburban Environments
(2023-12-08)
The Florida Department of Transportation (FDOT) utilizes an open-graded friction course
(OGFC), called FC-5, on all multi-lane roadways with a design speed of 50 mph or greater, except
for curb and gutter sections, to ...
Development of micelle delivery systems for cancer therapy
(2023-12-08)
Polymeric micelles have been investigated as nanomedicines for cancer treatment. They can target specific tissues, prolong circulation, and reduce side effects. These features make them a promising delivery system for ...